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EchoMS OPI Leakage Issue

What is the best way to determine if a recurrent OPI leak during standard operation is due to a faulty/ fouled OPI probe head or a fouled/damaged electrode or poor flow rate optimization?

Adapting a SCIEX high flow source for microflow LC

To set up a SCIEX high flow source for microflow LC (Turbo V ion source, DuoSpray source or IonDrive Turbo V ion source), first you must replace the wider bore electrodes with more narrow bore hybrid electrodes. Note with the OptiFlow Turbo V ion sources, there are...

Selecting the mobile phase for your assay and optimizing flow rates

High level method optimization considerations for Echo MS system

While an in-depth discussion of method development and optimization for the Echo® MS system is beyond the scope of a community post, here are some points to consider as part of the process: The maximum recommended ion spray voltage for prolonged electrode life is 5000...

Selecting the mobile phase for your assay and optimizing flow rates

Tips to maximize electrode lifetime for Echo MS system

While it’s easy to think of the Echo® MS system as an ultrafast LC system in front of the SCIEX Triple Quad 6500+ mass spectrometer, the system operates on fundamentally different principles. For this reason, it requires different routine maintenance to keep it...