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If you are working with complex assays that demand exceptionally selective quantitative and qualitative performance, sometimes even the most powerful LC-MS/MS technology can’t always cut it alone.
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Separation anxiety: Choosing the best approach to quantify the lipidome
Front-End Solutions for Lipid AnalysisWhich method should you choose? Lipids are a diverse group of compounds that serve many purposes. They are the basis for key biological entities including cell membranes, hormones, and lipoproteins and are involved in a variety...
The Latest and Greatest for Improving Lipidomic Analysis by Mass Spectrometry
Differential Mobility Separation (DMS) resolves multiple lipid classes within complex lipid matrices prior to MS analysis to enable more confident identification of lipid species and more accurate quantitation by MS/MS. Lipidomics research has progressed rapidly in...
The Ultimate Selectivity for Peptide and Protein Quantitation
There’s no doubt about it, biopharma drug development is experiencing phenomenal growth and presents a variety of challenges not experienced in small molecule development. Some of these challenges are in the selective and sensitive quantitation of peptides and...
5 Applications That Benefit from a New Dimension in Selectivity
Mass spectrometry can provide exceptional sensitivity, selectivity, resolution, throughput, and mass accuracy, but certain applications demand additional levels of selectivity. This is where differential ion mobility technology comes in. It delivers highly-selective,...
Transform the Analytical Power of Your SCIEX Mass Spec with SelexION Technology
If you are working with complex assays that demand exceptionally selective quantitative and qualitative performance, sometimes even the most powerful LC-MS/MS technology can’t always cut it alone.
5 Ways That SelexION Technology Will Address Your Biggest Analytical Challenges
If you are a scientist working with complex assays, finding a way to significantly improve selectivity of detection could solve some of your biggest analytical headaches. Are we right? If so, then you are in the right place. If you are confronted with assay...
The Science Behind SelexION Differential Mobility Spectrometry Technology
Scientists and analysts across all fields of testing and research are increasingly challenged by complex samples requiring advanced analytical selectivity. And where LC-MS/MS sensitivity alone is not enough to meet the demands of modern day quantitative performance, Differential Ion Mobility Spectrometry (DMS) has proven to be a valuable addition.
Simplify and Improve the Analysis of Lipid Molecular Species Using SelexION Technology
Analyzing lipids can be tricky. Lipids tend to have a wide variety of chemical structures, and this makes it virtually impossible to find one LC method that can resolve all lipid species. Therefore, multiple LC methods are often used. Also, there is widespread isobaric and isomeric overlap between different lipid classes and species, therefore separating lipid compounds, using an orthogonal separation prior to mass analysis is important.
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