Is Your Lab Prepared for Testing? The Global Supplement Market is Growing by SCIEX Community | 0 CommentsDon’t judge a nutritional supplement by its label, as often, government monitoring of ingredients begins after the product enters the consumer market1. Meanwhile, there may be additional additives not mentioned on the label as they are used to address supplement side effects. Such is the case in the United States where even though federal law requires supplements to carry a dietary supplement label or a substitutional term, monitoring begins once a supplement is on the market. In China meanwhile, the China Food and Drug Administration’s (CFDA) health product potential illegal additives list, clearly stipulates monitoring processes for additives in six different types of nutritional supplements including weight loss, blood sugar reduction, blood pressure reduction, anti-fatigue, sleep improvement and immune strengthening functions.Read Tech Note >
How to Detect Additives in Cosmetics Amongst Ever Changing Regulations by SCIEX Community | 0 CommentsIn today’s technical blog, I’m talking about the cosmetics industry so let’s get right to it. According to a Research and Market report, “The Global Cosmetic market was $460 billion USD in 2014 and is estimated to reach 675 billion USD by 2020, growing at a rate of 6.4%.”1 The U.S. leads the pack with a reported $62 billion in revenue earned in 20162. So, what am I getting at? We know earnings are strong and consumers like their products. But the question remains, are these products that you put on your skin, hair, and ingest safe? Such is the thinking of scientists like me and other chemists who are routinely tasked with detecting minimal levels of potentially harmful ingredients in personal care products against ever-changing global regulations.
A Mine of Quantitative Proteomic Information by SCIEX Community | 0 CommentsThe Aebersold group at ETH Zurich focuses on proteomics research, including the development of techniques to study the proteome as an integrated entity. In collaboration with SCIEX, the group established SWATH® Acquisition mass spectrometry, a data-independent acquisition (DIA) method capable of fragmenting multiple peptide species concurrently. The resulting comprehensive data set can be retrospectively re-mined, enabling maximum benefit to be derived from any study.
Delivering New Biologics to the Marketplace by SCIEX Community | 0 CommentsCharacterization and quantification of host cell proteins (HCPs) in biopharmaceutical development and manufacturing is a critical step to ensuring product safety. While this can be achieved using ELISA, mass spectrometry using the SCIEX TripleTOF® 6600 System is more specific and enables the identification and quantitation of each of the individual proteins present.
Bulletproof your clinical laboratory with rugged and reliable LC-MS/MS instrumentation (Clinical diagnostic blog) by Pierre Negri | Blogs, Clinical, Ion sourcesThe ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
Bulletproof your clinical laboratory with rugged and reliable LC-MS/MS instrumentation (Clinical research blog) by Pierre Negri | Blogs, Clinical, Ion sourcesThe ability to consistently achieve reproducible results on many complex samples across multiple days is critical to a routine clinical laboratory. Laboratories relying on analytical instrumentation require stability and robustness to perform a variety of screening and confirmatory assays with confidence. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the preferred analytical method in the clinical laboratory to reliably perform clinical testing as it provides best-in-class performance and reliability for the most challenging assays. LC-MS/MS offers the required levels of sensitivity and specificity for the detection and quantitation of molecules from complex biological samples, helping laboratories deliver highly accurate data for a variety of clinically relevant analytes across a wide range of assays.
Methods for electrode cleaning for Echo MS systems by John Gibbons | Blogs, Echo® MS+ system, PharmaDepending on the samples that you are running on the system, it is possible for the Echo MS electrode to become dirty or occluded over time. Below are two different cleaning strategies that will be helpful for you to maintain your system and keep your electrodes running well.
The myth of costly training: debunked. by Andrea Mueller | Blogs, Instrument maintenance, Optimizing Performance, Technology, TrainingAs analytical organizations grow, there is an even greater need to train scientists and operators more consistently to meet tight deadlines, handle increasing samples, and meet data quality expectations. A high rate of employee turnover also affects the productivity of labs worldwide. Consistent training helps today’s labs stay competitive, whether the goal is sample throughput, therapeutic development, or publication.
PFAS regulations – a journey around the globe by Gitte Barknowitz | Blogs, Environmental / IndustrialA few years ago, I was plotting along in my analytical job and keeping up-to-date with residue regulations took a considerable amount of time, but it was always manageable. Nowadays, we have PFAS.
Tackling mycotoxin testing: Harnessing mass spectrometry for safer foods and healthier futures by SCIEX Community | Blogs, Food / Beverage, Food and BeverageProduced by certain moulds, thriving in crops such as grain, nuts and coffee, mycotoxins have contaminated agriculture and food production industries for a long time. To intensify the challenge, mycotoxins are resilient, not easily broken down and ensuring the safety of food supply chains requires comprehensive solutions and we are here to share those solutions with you.
Enhancing omics-based mass spectrometry workflows with Electron-Activated Dissociation (EAD) by Rebekah Sayers | Blogs, Life Science ResearchElectron-Activated Dissociation (EAD) is transforming the fields of metabolomics and lipidomics by providing enhanced fragmentation techniques that offer deeper insights into molecular structures. In September, Technology Networks hosted a webinar, “Enhancing Mass-Based Omics Analysis in Model Organisms,” featuring Dr. Valentina Calabrese from the Institute of Analytical Sciences at the University of Lyon. Valentina shared her insights on improving omics-based mass spectrometry analysis for toxicology studies using model organisms, particularly in metabolomics and lipidomics. This blog explores the additional functionalities EAD offers, its benefits in untargeted workflows, its incorporation into GNPS and molecular networking, and the future role it could play in these scientific domains.
The economics of food testing: A strategic perspective for laboratory managers by Philip Taylor | Blogs, Food / Beverage, Food and BeverageIn today’s rapidly evolving food industry, the role of food testing laboratories has never been more critical. Ensuring the safety, quality, and authenticity of food products is paramount, and this responsibility falls heavily on the shoulders of laboratory managers. The economics of food testing—encompassing everything from high-throughput pesticide screening to advanced research on alternative protein sources—plays a pivotal role in shaping the operational efficiency and financial health of these laboratories.
Six benefits of remote support every laboratory should know by Andrea Mueller | Biopharma, Blogs, Environmental / Industrial, Food / Beverage, Food and Beverage, Forensic, Instrument maintenance, Life Science Research, Optimizing Performance, Pharma, Service, Support, Technology, TrainingImagine having a tech expert at your fingertips to solve computer issues or a fitness trainer guiding you through workouts from the comfort of your home. In today’s fast-paced world, the ability to provide and receive service and support remotely is no longer a luxury but a necessity. Whether it’s troubleshooting a software issue, repairing a device, offering customer assistance, or enjoying the convenience of telehealth as a private individual, remote capabilities have revolutionized how businesses operate and how individuals get help
Advancing immunopeptidomics for pancreatic cancer research with ZT Scan DIA by Katherine Tran | Blogs, Life Science ResearchPancreatic cancer remains one of the most fatal types of cancer, and the rates of occurrences and mortalities continue to be on a global rise.1,2 Recent statistics have reported that the diagnosis of pancreatic cancer is the eighth most common type of cancer and...