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Never Stop Learning with SCIEX University

Did you know that when you log into SCIEXUniversity, you have 24/7 access to educational tools? Simply click on the Support from SCIEX.com and select SCIEXUniversity. Here you will find more than 100 newly revamped courses developed by in-house experts, scientists, and researchers who, just like you, are interested in the next scientific breakthrough. Whether you are a beginner mass spec user or have years of experience, these online and on-site courses are designed with you, the user, in mind. What is more is that the course catalog offers self-paced training and certification programs to help you get better acquainted with software, instrumentation, and workflows

Fast and Simultaneous Analysis of Ethanol Metabolites and Barbiturates

While most analytes in forensic applications analyze well with positive ionization, there are analytes that show better ionization efficiency with negative ionization, for example, acidic compounds. These analytes include ethanol metabolites such as ethyl glucuronide (ETG), ethyl sulfate (ETS), and the barbiturates such as amobarbital, butabarbital, butalbital, pentobarbital, phenobarbital, and secobarbital.

It’s a Point and Click World with the X500B QTOF System for Biologics Characterization

Did you know the X500B QTOF system makes point and click workflows for Biologics Characterization possible on your mass spectrometer? The newly-designed SCIEX OS software interface brings to life fluid navigation and ease of use so you can keep moving forward on your scientific discoveries. In fact, it’s so simple to learn and operate that you and your team can be up and running faster than you might expect.

PPCP Detection in Drinkwater is no Match for the QTRAP® 5500

SCIEX is no stranger to drinking water analysis, and the Environmental Compendium once again addresses the topic in an application note which covers LC-MS/MS with Fast Polarity Switching.   Using the QTRAP® 5500, researchers were able to detect a large panel of Pharmaceuticals and Personal Care Products (PPCP’s) while performing fast positive/negative switching all from a single injection.  Method details go the distance in this application note, as five experiments were called into action for comparison.

Why traditional MS/MS falls short for ADCs and how electron-activated dissociation (EAD) changes the equation

Why traditional MS/MS falls short for ADCs and how electron-activated dissociation (EAD) changes the equation

Antibody-drug conjugates (ADCs) are among the most promising—and analytically demanding—modalities in biopharma today. By combining large, heterogeneous antibodies with chemically labile payloads and linkers, ADCs introduce a level of structural complexity that challenges conventional analytical workflows. It also poses the challenge that the very features you need to measure are often the easiest to lose during analysis.

Sterile but toxic: Cereulide detection in food matrices

Sterile but toxic: Cereulide detection in food matrices

In a recent webinar, Ming Gao, Ph.D., Senior Research Chemist at Mérieux NutriSciences, explored the growing challenge of cereulide contamination in food products and the analytical strategies needed to detect this heat-stable toxin at trace levels. The session examined how LC-MS/MS can help laboratories overcome the limitations of traditional microbiological screening and meet emerging regulatory requirements.

How SCIEX Now empowers mass spec users to work with more control, clarity and confidence

How SCIEX Now empowers mass spec users to work with more control, clarity and confidence

In this interview, Andy Wilcox, Senior Market Development Manager, Aftermarket and Software, speaks with Susanna Baqué, Senior Director of Global Customer Experience, about how SCIEX Now gives customers one connected digital workspace to manage instruments, reduce time spent searching for information, resolve issues faster and keep their laboratory running more efficiently and with greater confidence.

PFAS explained: What they are, why they matter, and what’s changing

PFAS explained: What they are, why they matter, and what’s changing

PFAS are increasingly at the center of regulatory change, scientific research, and industry discussion worldwide. As analytical capabilities improve and expectations around environmental responsibility continue to evolve, understanding the role PFAS play, and how they are being addressed, has never been more important. This blog provides an overview of what PFAS are, why they matter, and how responses from regulators and industry are changing.

Why electron-activated dissociation (EAD) improves sequence variant analysis in biopharma LC/MS workflows

In biopharmaceutical development, sequence variants (SV) are considered an inherent risk of producing complex proteins in living systems. Sequence variants are unintended changes to the amino acid sequence of a biotherapeutic and can be caused by errors in transcription or translation in the host cell, or cell culture and process conditions. Detailed analysis of SVs is important in process and product development to ensure the drug’s safety and efficacy. Even low‑level sequence variants can have significant implications for product quality, safety, and efficacy, making their accurate detection and characterization a critical requirement across development, process optimization, and regulatory submission.  

Getting PFAS right: Why sample preparation matters

Getting PFAS right: Why sample preparation matters

Ultra‑low reporting limits, expanding target lists, and the constant risk of background contamination mean that even small missteps before injection can compromise data integrity. PFAS can be introduced at nearly every stage of prep, from sampling containers and PPE to SPE cartridges, filters, solvents, and lab consumables, making contamination control as critical as analyte recovery.

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