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Guided optimization of MRM by infusion in SCIEX OS software
This short video walks through the use of the automated MRM optimization feature in SCIEX OS software for optimizing the compound dependent parameters for an MRM experiment using an infusion approach. Here, we infuse reserpine to demonstrate the key elements of MRM parameter optimization. RUO-MKT-18-12293-A
August 7, 2021
Guided optimization of MRM3 in SCIEX OS software
This short video walks through the use of the automated compound optimization feature in SCIEX OS Software for optimizing the parameters for an MRM3 experiment. Here, we use reserpine and walk through the elements of MRM3, highlighting the key steps of optimization along the way. For more information about how MRM3 on SCIEX QTRAP systems works, please […]
SCIEX OS software – configuration
This short video will take you through a tour of the Configuration module within SCIEX OS software. This is a great video to watch if you are just getting started with SCIEX OS and want to know more about configuring projects, user management, security, and other workstation set up considerations. You will see how easy […]
Calculated columns, flagging rules, and filtering
Get to the results you want to see in less time than you imagined Data processing software has become more than just a quantitative tool to tell us how much is in a sample. Now with the immense volumes of data being generated in high-throughput environments, there is an increase in demand for these software […]
Automatic outlier removal using SCIEX OS software
Advances in technology have resulted in a need for higher and faster sample throughput, with increasing number of measured analytes per sample – sometimes up into the 1000’s. A greater strain on necessary data analysis steps leads to a bottleneck of data processing and review for chromatographic peak integration, quality of calibration curve, and more. […]
Standard addition workflow – for quantification and calculating background levels
The method of standard addition is a quantitative analysis approach used in situations where matrix effects from complex samples contributes to the analytical signal. This makes it impossible to compare the analytical signal between sample and standard using a traditional calibration curve approach. The standard is spiked directly into aliquots of the sample matrix. This […]
- Bioanalysis/PK
- Data processing
- Pharma
- QTOF
- QTRAP / Triple Quad
- SCIEX information
- SCIEX OS software
- Technology
- ZenoTOF 7600 system
Tags: addition, calibrate, curve, job, machine, matrix, mode, model, object, research, sample, science, signal, software, spike, standard, style, used, way, work
Decision Rules in SCIEX OS software
Learn how Decision Rules in SCIEX OS software can be used during acquisition to take corrective actions on the sample queue. This will help you save time and reduce sample losses during acquisition. RUO-MKT-11-13239-A
Tags: acquisition, corrective, decision, queue, rule, sample, software, training
The AutoPeak integration algorithm, and how it can help reduce the headache of re-integrating data
With higher throughput demands on today’s mass spec quantitative applications, the bottlenecks affecting sample turnaround time are moving from data acquisition to data processing. Most lab environments like this can’t afford the time it takes to re-integrate missed peaks due to run retention time shifts or bad integrations due to matrix interferences. Also, regulations put […]
Can I merge multiple ion libraries within OneOmics suite for my SWATH acquisition proteomics analysis?
For targeted processing of SWATH acquisition proteomics data, ion libraries are used to provide the information on the proteins, peptides, fragment ions and retention time to be used. To get the most out of your SWATH acquisition data, it is often required to build larger ion libraries. The ability to merge multiple proteomic ion libraries […]
How do I add a retention time calibration protein to my SWATH acquisition ion library?
When processing SWATH acquisition data, you want to use a reasonably narrow time window to reduce the chance of incorrect peak integrations and to reduce data processing time. There are currently two strategies being employed today to adjust for differences between the retention times in the spectral ion libraries and the retention times observed in […]
- Data processing
- Life Science Research
- OneOmics
- Proteomics
- QTOF
- SCIEX information
- ZenoTOF 7600 system
Tags: calibrate, cloud, data, data file, ion, library, retention, retention time, software
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