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PFAS explained: What they are, why they matter, and what’s changing


PFAS are increasingly at the center of regulatory change, scientific research, and industry discussion worldwide. As analytical capabilities improve and expectations around environmental responsibility continue to evolve, understanding the role PFAS play, and how they are being addressed, has never been more important. This blog provides an overview of what PFAS are, why they matter, and how responses from regulators and industry are changing.

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June 17, 2026


Pesticide residue testing in food: Supporting confident and compliant analysis


Pesticides are widely used in agriculture to protect crops and maintain yield, but their presence in food must be carefully monitored. To safeguard consumers, regulatory authorities worldwide set maximum residue limits (MRLs), often at very low concentrations and across a wide range of compound classes.

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June 11, 2026


Why capillary electrophoresis still matters in modern biopharma


Explore why capillary electrophoresis remains essential for high resolution, confident analytics across modern biopharma modalities, from proteins to mRNA and gene therapies

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June 9, 2026


Where does capillary electrophoresis fit across drug development?


Capillary electrophoresis (CE) is not confined to a single point in the drug development lifecycle. Its value comes from the ability to deliver high‑resolution, reproducible separations that remain relevant as analytical questions evolve, from early discovery through late‑stage development and lot release.

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Introducing the SCIEX resource hub: All your resources, one place


Finding the right information shouldn’t slow you down. Whether you’re troubleshooting your mass spec, learning something new, or optimizing performance, access to the right resources at the right moment makes all the difference.

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May 27, 2026


Why middle‑down and subunit MS analyses powered by EAD are transforming biopharmaceutical characterization


As an analytical strategy, middle-down mass spectrometry (MS) workflows characterize biotherapeutic proteins by analyzing large, digested protein fragments or defined subunits, rather than fully intact proteins (top-down) or digested peptides (bottom-up). A middle-down strategy combines the strengths of top-down and bottom-up approaches by delivering high sequence coverage and structural specificity while maintaining relatively simple sample preparation. In practice, middle-down analysis enables accurate mass measurement, rapid sequence confirmation, and localization of key post-translational modifications (PTMs) on protein subunits that are directly relevant to product quality.

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May 15, 2026


Why electron-activated dissociation (EAD) improves sequence variant analysis in biopharma LC/MS workflows


In biopharmaceutical development, sequence variants (SV) are considered an inherent risk of producing complex proteins in living systems. Sequence variants are unintended changes to the amino acid sequence of a biotherapeutic and can be caused by errors in transcription or translation in the host cell, or cell culture and process conditions. Detailed analysis of SVs is important in process and product development to ensure the drug’s safety and efficacy. Even low‑level sequence variants can have significant implications for product quality, safety, and efficacy, making their accurate detection and characterization a critical requirement across development, process optimization, and regulatory submission.  

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April 29, 2026


How NFD improves impurity detection and peak integration in CE SDS workflows


CE‑SDS remains a cornerstone assay for characterizing fragmentation, aggregation, and product‑related impurities in therapeutic proteins. UV detection has been the long‑standing standard. However, it frequently struggles with baseline noise, limited sensitivity for minor fragments, and subjective integration.

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April 28, 2026


What´s new in SCIEX Now – spring release 2026


At SCIEX, innovation doesn’t stop at instruments; it extends to how you interact with your LC-MS/MS or CE systems every day. That’s why we’re excited to introduce the SCIEX Now spring 2026 improvements: a set of meaningful enhancements shaped directly by your feedback.

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April 23, 2026


The troubleshooting tool LC-MS users have been waiting for


In today’s fast-paced analytical laboratories, uptime is not just important; it is mission-critical. Whether you are running high-throughput bioanalysis, environmental testing, or pharmaceutical workflows, every minute of LC-MS downtime can impact productivity, data quality, and timelines.

That is why we are excited to introduce a smarter and faster way to troubleshoot.

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