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Getting PFAS right: Why sample preparation matters
Ultra‑low reporting limits, expanding target lists, and the constant risk of background contamination mean that even small missteps before injection can compromise data integrity. PFAS can be introduced at nearly every stage of prep, from sampling containers and PPE to SPE cartridges, filters, solvents, and lab consumables, making contamination control as critical as analyte recovery.
Tags: bag, blog, brush, clean, clean beaker, cleaning, di water, job, period, PFAS, place qj, position, rinse, room, Sample Prep, solution, space, tap, tap water, time, use, water, water rinse, white, wipe
April 17, 2026
CE‑SDS in monoclonal antibody therapeutic development
In monoclonal antibody (mAb) development, assessment of purity and integrity of the protein in question is critical. CE‑SDS is the gold standard assay and is routinely run from analytical development through QC and lot release. It’s trusted because it consistently delivers quantitative, size‑based insight into purity and fragmentation, and it fits naturally into regulated environments.
Tags: BioPhase 8800, CD-SDS, NFD
March 31, 2026
EAD vs. ETD: Choosing the right fragmentation technique for small molecule Met ID studies
In drug discovery and development, Metabolite Identification (Met ID) plays a critical role in understanding biotransformation pathways, ensuring safety, and meeting regulatory requirements. Advanced mass spectrometry techniques have revolutionized this process, particularly through electron-based fragmentation methods such as Electron Activated Dissociation (EAD) and Electron Transfer Dissociation (ETD). While both techniques leverage electron interactions to generate informative fragment ions, they differ significantly in mechanism, performance, and suitability for Met ID workflows.
Tags: EAD, ETA, Met ID, Metabolite Identification
March 25, 2026
Predictable uptime starts with a predictable service strategy
In analytical laboratories, performance is not optional. Whether supporting regulated pharmaceutical workflows, high-throughput CRO operations, clinical reporting, or food and environmental testing, your mass spectrometry and capillary electrophoresis systems are critical to productivity, compliance, and scientific confidence.
- Biopharma
- Blogs
- Clinical
- Environmental / Industrial
- Food / Beverage
- Forensic
- Life Science Research
- Pharma
- Service
- Support
- Technology
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March 18, 2026
Alkaloids in food: Why robust testing matters How SCIEX supports food safety laboratories
Naturally occurring toxins are an unavoidable reality of today’s global food supply, and among them, alkaloids represent one of the most analytically challenging and safety‑critical compound classes. Produced by plants as natural defence mechanisms, alkaloids can unintentionally enter food through contamination, co‑harvesting, or adulteration, posing serious risks to consumer health and regulatory compliance.
Tags: Alkaloids
PFAS in textiles: What laboratories are starting to uncover
Waterproof jackets. Stain-resistant shoes. Easy-clean fabrics are marketed as “performance.” Behind those everyday claims sits a class of chemicals now reshaping regulation, brand accountability, and laboratory science: PFAS.
Tags: bag, brush, clean, clean beaker, cleaning, di water, job, period, PFAS, place qj, position, rinse, room, solution, space, tap, tap water, textiles, time, use, water, water rinse, white, wipe
February 25, 2026
Advancing bioanalysis with SCIEX: Insights from three decades of innovation
For decades, SCIEX has been part of bioanalytical innovation, empowering scientists in pharma and biopharma to push the boundaries of sensitivity, accuracy, and throughput. Across complex workflows and increasingly challenging therapeutic modalities.
Tags: bioanalysis
February 18, 2026
The rise of TFA in Europe’s cereals: How SCIEX and Phenomenex empower accurate detection of this “forever chemical”
Trifluoroacetic acid (TFA) is emerging as one of the most concerning ultrashort-chain PFAS in Europe’s food supply – particularly in cereals, a staple consumed daily by millions. A report from PAN Europe reveals a widespread and largely unmonitored contamination trend that raises serious questions about food safety, regulatory blind spots, and future monitoring strategies.
Tags: TFA, Trifluoroacetic acid
January 29, 2026
PFAS FAQ’s: Ask our experts
PFAS analysis is complex, but expert guidance doesn’t have to be. In this episode of our ‘Ask the PFAS expert series’, we’re joined by Michael Scherer, Application Lead for Food and Environmental, to answer the most pressing questions in PFAS analysis. From why LC-MS/MS systems are the gold standard for analyzing diverse PFAS compounds, to which EU methods deliver reliable results for drinking water, and to practical steps to prevent contamination, Michael shares actionable insights to help laboratories achieve accuracy, consistency, and confidence in their workflows.
Tags: bag, brush, clean, clean beaker, cleaning, di water, job, period, PFAS, PFAS Ask the Experts, place qj, position, rinse, room, solution, space, tap, tap water, time, use, water, water rinse, white, wipe
January 23, 2026
What do scientists really think about EAD for Met ID?
During an LC-MS/MS experiment, traditional fragmentation techniques like collision-induced dissociation (CID) have long been the gold standard. Electron-activated dissociation (EAD) is emerging as a transformative tool that enhances structural elucidation, particularly for complex or labile metabolites.
Tags: analysis, analytical, computer, data, dissociate, drug, Drug development, elucidate, fragmentation, identification, information, job, knowledge, machine, research, science, structural, technology, use, work
January 8, 2026
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