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Unveiling the power of ZT Scan DIA: Insights from Ludwig Sinn’s presentation at World HUPO Congress 2024
In a recent presentation at the World HUPO Congress 2024, Ludwig Sinn from the Ralser lab shared exciting advancements in proteomics research, focusing on the innovative ZT Scan DIA acquisition modes developed in collaboration with SCIEX. Let us explore the key highlights and benefits of this innovative technology.
Tags: bag, brush, Charité-Universitätsmedizin, clean, clean beaker, cleaning, di water, glycoproteomics, high throughtput proteomics, job, Ludwig Sinn, period, place qj, position, Ralser lab, rinse, room, solution, space, tap, tap water, time, use, water, water rinse, white, wipe, ZenoTOF 7600 system, ZT Scan DIA
February 7, 2025
Exploring the power of ZT Scan DIA
In a recent presentation, Tim Heymann from Mann Lab at the Max Planck Institute of Biochemistry shared his first impressions of ZT Scan DIA, the novel data-independent acquisition strategy from SCIEX, highlighting its innovative approach and significant benefits for proteomics research. Let’s dive into the key points from his insightful talk.
Tags: bag, brush, clean, clean beaker, cleaning, di water, high throughtput proteomics, job, Mann Lab, Max Planck Institute of Biochemistry, period, phosphoproteomics, place qj, position, rinse, room, solution, space, tap, tap water, Tim Heymann, time, use, water, water rinse, white, wipe, ZenoTOF 7600+ system, ZT Scan DIA
Inside the box: Complementary fragmentation with LC-MS for Metabolite Identification
Liquid chromatography-mass spectrometry is commonly used for Met ID but confident soft spot identification is not always possible. Imagine the advantage of unambiguous metabolite identification using liquid chromatography-mass spectrometry (LC-MS) reducing the need for additional safety testing during drug discovery. Quickly and easily generate the information you need using routine assays that are robust and efficient, enabling confident decision-making while also saving time and money.
Tags: bag, Biosecure act, brush, CDMO, clean, clean beaker, cleaning, CRO, di water, job, period, Pharma, place qj, position, rinse, room, solution, space, tap, tap water, time, use, water, water rinse, white, wipe
The whys behind the dos and don’ts of oligonucleotide analysis
We know that LC-MS oligonucleotide analysis can have its share of challenges—challenges with sensitivity, challenges with adduct formation and challenges with data analysis, to name just a few. That’s why this blog takes a closer look at the dos and don’ts of this type of analysis and explores some keys to success. It also explains why following these simple rules can vastly improve your oligonucleotide characterization and quantitation efficiency and success.
Tags: 7500+, adduct, Biopharma, ion-pairing, oligonucleotide, oligonucleotide analysis, sensitivity, ZenoTOF 7600 system
February 1, 2025
Tips and tricks from our application experts: AAV analysis with CE
Peter Holper, Staff Applications Scientist at SCIEX, US, shares his tips and tricks on AAV analysis using CE with the BioPhase 8800 system and the PA 800 Plus system.
Tags: AAV, bag, blog, brush, cgt, clean, clean beaker, cleaning, di water, Holper, job, period, place qj, position, rinse, room, solution, space, tap, tap water, time, use, water, water rinse, white, wipe
January 24, 2025
Pharma perspectives: The influence of LC-MS innovation on drug development outsourcing
It is no secret that (bio)pharmaceutical research and development is complex, both scientific and regulatory processes. Working for a contract research organization and more recently for SCIEX has provided an interesting perspective on trends the market experiences that affect many of us.
Tags: Biosecure act, CDMO, company, complex, computer, contract, contract research, CRO, development, drug, group, information, job, learning, machine, machine learning, mass, new, organization, Pharma, research, science, technology, work
January 13, 2025
Overcoming uncertainty in your PFAS analysis
Just like gum on the bottom of a shoe, the existence of per- and poly-fluorinated alkyl substances (PFAS) in our environment is a sticky one. If you’re in the field of environmental testing, then you’re all too familiar with the threat these substances have on public health. While we have learned a lot about them over the years, there is still much more to understand. With the right detection methods, we can gather the information we need to empower us to make informed decisions on reducing the risks they impose.
Tags: blog, compound, computer, confidence, confidence scale, data, detection, exist, HRMS, information, know, knowledge, low, machine, mass, method, PFAS, place, research, science, testing, use, used, work
December 19, 2024
6 Signs it’s time for a new vendor
A lab’s success depends on many factors from instrument quality to efficient operations, including being partnered with the right vendor. A vendor is more than just a supplier. They should provide you with a high-level quality of support in maximizing the lifespan and performance of your systems, reducing downtime, enhancing ROI and more. How do you know if you’re partnered with the right one? Here are six signs it might be time to find someone new.
Tags: business, car, development, instrument, job, machine, money, OEM, part, professional, provider, quality, right, service, service provider, sign, study, support, system, team, video, work, workflow support
December 12, 2024
Plasmid manufacturing: Setting up your CGT programs for success
Plasmid DNA serves a variety of purposes, from critical starting material for proteins, mRNA, viral vectors, and drug substances. Below, Dr. Emma Bjorgum, the Vice President of Client Services of the DNA Business Unit at Aldevron and an expert in plasmid manufacturing, provided insights into the process and an outlook on the future.
Tags: AAV, Aldevron, blog, cell and gene therapy, CGE, cgt, CRISPR, DNA, mrna, plasmid, plasmid manufacturing
November 15, 2024
Understanding PFAS and its impact on U.S. drinking water
In recent years, per- and polyfluoroalkyl substances (PFAS), often referred to as “forever chemicals,” have become a growing topic of interest due to their persistence in the environment and potential health risks. These synthetic compounds have been widely used in various industrial applications and consumer products since the 1940s. PFAS can be found in the air, soil, and water, and studies have shown that most people have detectable levels of PFAS in their bloodstream. One of the main exposure pathways for humans is through drinking water, particularly in communities located near industrial sites, military bases, or areas where firefighting foam has been used.
Tags: drinking, government, health, PFAS analysis, PFAS Drinking Water, PFAS testing, PFAS US, water
October 31, 2024
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