6 Signs it’s time for a new vendor by Michael Wonski | Dec 12, 2024 | Blogs, Instrument maintenance, Optimizing Performance, TechnologyA lab’s success depends on many factors from instrument quality to efficient operations, including being partnered with the right vendor. A vendor is more than just a supplier. They should provide you with a high-level quality of support in maximizing the lifespan and performance of your systems, reducing downtime, enhancing ROI and more. How do you know if you’re partnered with the right one? Here are six signs it might be time to find someone new.
Source optimization by Trang Nguyen | Sep 11, 2023 | Ion sources, Optimizing Performance, QTRAP / Triple Quad, Questions, SCIEX OS softwareHello. I am setting up a new development method for analyzing toxic chemicals.
Assess the performance of the Echo® MS system by Christie Hunter | Apr 6, 2022 | Echo MS, Optimizing Performance, SCIEX information, TechnologyTo obtain the best, most reproducible results using the Echo MS system, it is important to select the best solvent for your analyte and matrix and to ensure the flow rate is optimized for your solvent. Please review this flow rate optimization community post to...
Standard mixture for bare fused silica capillary. by Jose Rodriguez-Martinez | Feb 15, 2022 | Biopharma, CE, Data acquisition, Optimizing Performance, QuestionsHi, is there a recommended standard mixture to evaluate the performance of CZE runs in a bare fused capillary with UV/Vis detector? Thanks.
How to optimize sample plating to run Echo MS system in ‘Fast acquisition mode’ by Mackenzie Pearson | Jan 31, 2022 | Data acquisition, Echo MS, Optimizing Performance, Pharma, SCIEX information, TechnologyThe Echo MS system can acquire data extremely rapidly, at 1 second per sample. To achieve this speed, it should be ensured that there is adequate time between ejections for the analyte signal to return to baseline between ejections. Plating your samples such that you...
Selecting the mobile phase for your assay and optimizing flow rates by Mackenzie Pearson | Jan 31, 2022 | Data acquisition, Echo MS, Optimizing Performance, Pharma, SCIEX information, TechnologyTo obtain the best, most reproducible results with Echo MS system, it is important both to select the best solvent for your analyte and matrix and to ensure the flow rate is optimized for your solvent. Considerations for solvent selection: The Echo MS system is...
Using the Skyline / Panorama AutoQC tools for continuous monitoring your TripleTOF system performance by Christie Hunter | Dec 17, 2021 | Data acquisition, Life Science Research, Optimizing Performance, Proteomics, QTOF, SCIEX information, SkylineThe Skyline team has developed a nice pipeline for evaluation of LC-MS/MS performance over time for MS systems in the research lab environment. To help you use this solution, we have set up two Skyline Documents that you can use for continuous system monitoring....
sMRM Pro Builder template tutorial by Mackenzie Pearson | Nov 15, 2021 | Data processing, Data Visualization, How-to videos, Life Science Research, Lipidomics, Metabolomics, Optimizing Performance, QTRAP / Triple Quad, ResultsThe sMRM Pro Builder template is an Excel-based tool that can help you implement large panels of analytes in your lab. The Excel sheet will take your preliminary experimental results and compute retention times, retention time window widths and dwell time weighting to optimize your targeted assay.
Files for running the SWATH acquisition performance kit – ion library, performance trackers by Christie Hunter | Sep 20, 2021 | Data processing, Life Science Research, Optimizing Performance, Proteomics, QTOF, SCIEX information, ZenoTOF 7600 systemThe FASTA file required for use with the SWATH acquisition performance kit installs with ProteinPilot software or is available within OneOmics suite. Download this SWATH acquisition ion library for use with the SWATH acquisition performance kit Human2D_SOP_PepCalMix_...
Troubleshooting low flow LC – LC-MS peak area is lower than expected by Christie Hunter | Sep 20, 2021 | Data acquisition, LC, Life Science Research, Optimizing Performance, Proteomics, SCIEX informationSymptom: LC-MS peptide peak are is smaller than expected in PepCalMix Test Test: Use PepCalMix Infusion tests to determine if it is a problem with LC or MS Solution: First perform the SCIEX recommended performance tests using infusion on your MS system. If these...