A lab’s success depends on many factors from instrument quality to efficient operations, including being partnered with the right vendor. A vendor is more than just a supplier. They should provide you with a high-level quality of support in maximizing the lifespan and performance of your systems, reducing downtime, enhancing ROI and more. How do you know if you’re partnered with the right one? Here are six signs it might be time to find someone new.
Optimizing Performance
Optimizing Performance
Source optimization
Hello. I am setting up a new development method for analyzing toxic chemicals.
Assess the performance of the Echo® MS system
To obtain the best, most reproducible results using the Echo MS system, it is important to select the best solvent for your analyte and matrix and to ensure the flow rate is optimized for your solvent. Please review this flow rate optimization community post to...
Standard mixture for bare fused silica capillary.
Hi, is there a recommended standard mixture to evaluate the performance of CZE runs in a bare fused capillary with UV/Vis detector? Thanks.
How to optimize sample plating to run Echo MS system in ‘Fast acquisition mode’
The Echo MS system can acquire data extremely rapidly, at 1 second per sample. To achieve this speed, it should be ensured that there is adequate time between ejections for the analyte signal to return to baseline between ejections. Plating your samples such that you...
Selecting the mobile phase for your assay and optimizing flow rates
To obtain the best, most reproducible results with Echo MS system, it is important both to select the best solvent for your analyte and matrix and to ensure the flow rate is optimized for your solvent. Considerations for solvent selection: The Echo MS system is...
Using the Skyline / Panorama AutoQC tools for continuous monitoring your TripleTOF system performance
The Skyline team has developed a nice pipeline for evaluation of LC-MS/MS performance over time for MS systems in the research lab environment. To help you use this solution, we have set up two Skyline Documents that you can use for continuous system monitoring....
sMRM Pro Builder template tutorial
The sMRM Pro Builder template is an Excel-based tool that can help you implement large panels of analytes in your lab. The Excel sheet will take your preliminary experimental results and compute retention times, retention time window widths and dwell time weighting to optimize your targeted assay.
Files for running the SWATH acquisition performance kit – ion library, performance trackers
The FASTA file required for use with the SWATH acquisition performance kit installs with ProteinPilot software or is available within OneOmics suite. Download this SWATH acquisition ion library for use with the SWATH acquisition performance kit Human2D_SOP_PepCalMix_...
Troubleshooting low flow LC – LC-MS peak area is lower than expected
Symptom: LC-MS peptide peak are is smaller than expected in PepCalMix Test Test: Use PepCalMix Infusion tests to determine if it is a problem with LC or MS Solution: First perform the SCIEX recommended performance tests using infusion on your MS system. If these...