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Page 52 of 61
Looking to Quantify and Identify Pesticides in your Food Samples?
Visit our offices on any given day, and you are likely to discover researchers putting mass spectrometry to the test. The hum of the mass spectrometer is as common as conversations as scientists are tasked with developing methods that can be applied in real-world lab scenarios. In this case, André Schreiber SCIEX, Concord, Ontario, Canada, detailed, Comprehensive Quantitation and Identification of Pesticides in Food Samples Using the SCIEX UltraLC 100* and the SCIEX QTRAP® 4500 System.
Tags: biotherapeutic development, blaze, charge, company, couple, development, Food / Beverage, job, machine, mass, money, new, number, power, protein, rapid, system, technology, time, variant, work
January 25, 2017
Discover the New X500B QTOF System, the Simpler, Faster Path to Biologics Characterization Answers
Have you ever wished for a compact instrument that delivers expert-level answers to your most complex biotherapeutic characterization challenges faster and easier than what you are doing now? At SCIEX, we recognize that even expert users want easier ways to perform daily characterization tasks and get great results every time. That’s why we set out to develop the X500B QTOF system: a robust and reliable new instrument and software solution that reduces complexity and simplifies biologics characterization workflows so every scientist can get expert-level results
Tags: Biopharma, biotherapeutic development, blaze, charge, company, couple, development, job, machine, mass, money, new, number, power, protein, rapid, system, technology, time, variant, work
January 24, 2017
How to Achieve Higher Sensitivity with Hybrid Immunoaffinity LC-MS Assays
Protein-based biotherapeutics, including monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs) are a growing component of pharmaceutical companies’ drug pipelines. The growth of ADCs in particular is due to their ability to selectivity target and deliver a potent molecule to a cancer cell based on a specific tumor marker. In order to support this growing class of new drug molecules, robust and reliable bioanalytical methods are required. While ligand binding assays (LBAs) like ELISA have been the most popular platform for biotherapeutic quantitation, bioanalytical scientists have been increasingly adopting hybrid LBA/LC-MS methods in this area.
Tags: Biopharma, biotherapeutic development, blaze, charge, company, couple, development, job, machine, mass, money, new, number, power, protein, rapid, system, technology, time, variant, work
January 10, 2017
The Application of Research Grade MetabolitePilot™ Software for the Determination of the Catabolic Peptide Products of Exenatide
The stability of peptide and protein biotherapeutics directly impacts their pharmacokinetic profile, efficacy, and safety. It is therefore essential to characterize the stability of a given bio-therapeutic including both in-vivo and in-vitro catabolism, thereby providing a fundamental understanding of potential metabolic soft-spots. To facilitate an automated accurate mass LC-MS workflow for the detection and confirmation of peptide biotransformations and […]
Tags: Biopharma, biotherapeutic development, blaze, charge, company, couple, development, job, machine, mass, money, new, number, Pharma, power, protein, rapid, system, technology, time, variant, work
January 9, 2017
LC-MS/MS Screening of 64 New Psychoactive Substances Using Dried Blood Spots
There is a lot you can tell from a droplet of blood as it’s snapshot of what could be present in a body at any given moment. In the following application note, LC-MS/MS Screening of 64 New Psychoactive Substances Using Dried Blood Spots, researchers did just that as they used dried blood spots (DBS) opposed to the […]
Tags: biotherapeutic development, blaze, charge, company, couple, development, job, machine, mass, money, new, number, power, protein, rapid, system, technology, time, Toxicology, variant, work
December 16, 2016
LC-MS/MS Analysis of Emerging Food Contaminants
Ever wish you had access to the most up to date application methods but don’t know where to find them? The Food and Beverage Compendium is your one-stop resource for research notes ranging from pesticides, allergens, and antibiotics to mycotoxins, vitamins, and packaging. An example of what you can find inside includes the detection of pesticide 1080 […]
Tags: biotherapeutic development, blaze, charge, company, couple, development, Food / Beverage, job, machine, mass, money, new, number, power, protein, rapid, system, technology, time, variant, work
Is Your Beverage Truly 100% Fruit Juice?
There is nothing like the flavor of fruit juice whether freshly squeezed or made from concentrate to clench your thirst, except when it’s not 100 percent juice after all. As the following tech note, “Authenticity Assessment of Fruit Juices using LC-MS/MS and Metabolomic Data Processing,” (pgs.135-141) points out, such substances have become a likely target […]
Tags: biotherapeutic development, blaze, charge, company, couple, development, Food / Beverage, job, machine, mass, money, new, number, power, protein, rapid, system, technology, time, variant, work
Superbugs, Antibiotic Resistance, and the QTRAP® 6500+ System
‘Superbugs’, or bacteria that have developed antibiotic resistance as a result of adapting to the drugs used in their treatment, are dangerous infections that doctors struggle to stop from spreading. Even common infections such as urinary tract infections and pneumonia are susceptible to developing antibiotic resistance as bacteria can evolve quickly and share freely with […]
Tags: biotherapeutic development, blaze, charge, company, couple, development, job, machine, mass, money, new, number, Pharma, power, protein, rapid, system, technology, time, variant, work
December 15, 2016
Keep your system running at optimal performance with the SWATH acquisition performance kit
Standards, Protocols, and Templates for Generating your Best Quantitative Proteomics Data
If you are just starting out as a proteomics researcher using mass spectrometry, the workflow can seem particularly daunting. How do you know if your system is set up correctly? How do you know if you are getting the best data possible? And if you are a seasoned proteomics researcher, how do you know if your system is still running at peak performance from one study to the next?
Tags: method, ProteinPilot Software, Proteomics
December 12, 2016
Vice President Biden Announces Agreement Naming Children’s Medical Research Institute’s ProCan Lab to the ‘Cancer Moonshot’ Initiative
A key goal of the ‘Cancer Moonshot’ initiative is the advancement of precision medicine, with the goal of making more targeted therapies available to more cancer patients. And researchers believe that the time is right, with the new technological innovations, the new insight into the biology of cancer and big improvements in the handling of ‘big data.’
Tags: application, company, computer, different, form, guide, information, ion, job, machine, mass, method, option, Proteomics, research, science, sensitivity, system, time, triple, work
December 6, 2016
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