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Page 20 of 61

Rescheduling a Schedule I substance, and the Delta-8 controversy


Did you know that in the US, drugs and other chemicals are classified into 5 distinct categories depending on the drug’s acceptable medical use and its potential for abuse or dependency?  Drugs federally classified as Schedule I substances by the US Drug Enforcement Administration (DEA) are considered to have the highest potential for abuse and for creating severe psychological and/or physical dependence. In addition to heroin, LSD and MDMA (ecstasy), cannabis is classified as a Schedule I substance in the Controlled Substance Act of 1970, which means it has no approved medical usage.

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December 17, 2021


Using the Skyline / Panorama AutoQC tools for continuous monitoring your TripleTOF system performance


The Skyline team has developed a nice pipeline for evaluation of LC-MS/MS performance over time for MS systems in the research lab environment.  To help you use this solution, we have set up two Skyline Documents that you can use for continuous system monitoring. These can be used for monitoring your system performance at any […]

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How does automatic calibration work on the QTOF, TripleTOF and ZenoTOF systems?


When you think about calibration of a mass spectrometer, there are actually two aspects to consider. There is the accuracy of the calibration (that it is correct when calibration is performed) and the stability or precision of the mass calibration (that it remains correct over time). For calibration precision or stability in quadrupole Time of […]

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December 15, 2021


How do I check the quality of the Auto Retention Time Calibration used in my Extractor processing?


When using the Auto-Calibration option in Extractor, a set of retention time calibration peptides will be determined automatically from the library and used for RT calibration. To determine how the fit looks for the calibration on each datafile, follow these steps. Browse to the folder or project that contains the Extractor analysis for your experiment […]

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PFAS testing: solid phase extraction vs. direct injection methods


US Environmental Protection Agency (EPA) and Department of Defense (DoD) methods for testing per- and polyfluoroalkyl substances (PFAS) in drinking water require using solid phase extraction (SPE). SPE has been used extensively in environmental contaminant analysis both for concentrating large sample volumes (improving method sensitivity) and removing matrix interferences (sample cleanup).

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December 14, 2021


Uploading data for use in OneOmics suite


There are two options for data storage when working with the OneOmics suite. You can store your data either within the SCIEX Cloud platform in the Data Store, or you can store data in BaseSpace (Illumina) and link your BaseSpace account with the SCIEX Cloud platform. CloudConnect for PeakView software 2.2 is used to upload […]

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Visualizing SWATH acquisition results in CloudConnect


CloudConnect in PeakView software 2.2 enables both the upload of data files to the OneOmics suite as well as the download of SWATH acquisition results files for viewing. This post will describe how to download and visualize the results from Extractor processing, so that you can view your raw XIC data for the quantified proteins […]

December 13, 2021


Getting access to demo data and other files for learning the OneOmics suite


In order to help you get proficient in using the OneOmics suite workflows, we have provided some demo datasets along with numerous other valuable files and supporting information to help you get started. Once you get access to your SCIEX Cloud account and can view your SCIEX Data Store, you will notice that there is […]

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General source/gas settings to use when starting method development


Here, we provide a quick reference for the source/gas settings to use at various flow rates with Turbo V, IonDrive Turbo V and OptiFlow Pro ion sources that come with the various SCIEX mass spectrometers. While performing a full source/gas optimization can provide the best sensitivity, the parameters presented here will generally suffice for routine […]

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December 5, 2021


Cannabis legalization in the UK and the Cannabis Industry Council (CIC)


The legalization of cannabis in the UK is a hot topic as public demand continues to rise. While the UK legalized medical cannabis in late 2018, doctors have so far been reluctant to issue prescriptions.

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November 23, 2021


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