Dr. David Wishart, Departments of Biological Sciences and Computing Science, University of AlbertaCanada’s TMIC is an internationally-recognized leader in metabolomics, providing tools and resources that are used by laboratories around the world. The center offers...
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New features in OneOmics suite
I just wanted to thank the readers here, both the OneOmics suite users who’ve shared their time and watched OneOmics grow, and for all the talented developers and scientists who’ve made OneOmics suite what it is today.
Assess the performance of the Echo® MS system
To obtain the best, most reproducible results using the Echo MS system, it is important to select the best solvent for your analyte and matrix and to ensure the flow rate is optimized for your solvent. Please review this flow rate optimization community post to...
Merging two FASTA files
There is an easy way to merge two FASTA files together. Open notepad and type this string: type %*>"newfile.fasta" Enter any name for the FASTA file between the quotes. Save the file as: Merge FASTA files.bat Copy the two files you want to merge into the same...
Intabio acquisition expands SCIEX portfolio of impactful solutions to accelerate biotherapeutic development
Due to the nature of their production, biotherapeutics are difficult to manufacture. Growth conditions, purification protocols and formulation requirements can introduce unintended modifications into the protein structure that may affect its efficacy and safety.
Breaking down the SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP® Ready
Sensitivity and robustness carry different meanings in the world of mass spectrometry. Generally, sensitivity refers to an instrument’s ability to achieve lower limits of detection (LOD). Robustness, on the other hand, refers to an instrument’s ability to consistently...
Importing acquisition methods from Analyst software to SCIEX OS software
The SCIEX Triple Quad 7500 system is the first nominal mass instrument to be released completely on SCIEX OS software. Moving to a new software solution can be time consuming with the need to transfer numerous methods to the new platform. SCIEX OS software helps...
The honey sting
As a consumer it’s hard for me not to feel inundated with claims that our food is “all-natural” or “chemical-free” or that we should buy certain “superfoods” for their health benefits. We read labels and trust that the product we are buying is what we are truly...
Innovation that’s blasting through limitations in explosive detection
Mass spectrometry’s important role in identifying explosives The need for rapid explosive detection is now an unfortunate reality. The remit is multifaceted. The first is for preventative purposes, to protect us from any threat to life. The second is in the...
A new generation of therapeutic modalities
There are over 7,000 genetic diseases that could potentially be cured using gene therapy. Rare metabolic diseases, autoimmune disorders, cardiovascular disease and cancers are some of the top disease classes that can be addressed with gene therapies. With over 1,000...
Enhancing Biologics with CESI-MS Characterization
Comprehensive characterization of a biologic requires analysis at both the intact and digest levels, but these analyses can be complex and cumbersome. For example, with conventional liquid chromatography separations, researchers are often left with limited information...
Keeping Up with Synthetic Cannabinoids Using Mass Spec
Facts about Synthetic Cannabinoids and why you need to pay attention to evolving science
Mass Spectrometry Helps Researchers Solve a Mystery about Type 2 Diabetes Drug
This is an article from November 21, 2013. We thought it was an interesting story to share with you on this World Diabetes Day.
For the research conducted by the Australian and Canadian researchers, the analysis at the molecular level was optimized on SCIEX instrumentation, including the SCIEX TripleTOF® 5600 and the SCIEX QTRAP® 5500 system
Top Three Ways SCIEX has fun with Halloween Candy
Halloween is the time for lots of trick or treats ranging from chocolate bars to lollipops and oh so good candy corn. However, come October 31, it is time to mind sneaky ingredients that have the best disguise of all. From pork extracts, artificial sweeteners, to stuff that is hard to pronounce, SCIEX digs up some of our recent Food and Beverage studies for some ghoulishly good fun.
The Top Ten Things Scientists Think about on Halloween
The Top Ten Things Scientists Think about on Halloween
Analyze Large Omic Data Sets with Cloud Computing and See What More You Can Accomplish
Our scientific world is expanding. With each passing day, new discoveries are made, old discoveries are verified, and more data are generated. Large data sets are now the norm for omics experiments such as genomics, transcriptomics, proteomics, and metabolomics....
Simultaneous Detection of Multiple Species in Meat Using LC-MS/MS Technology
Smart food shopping starts with labels. However, what if we told you the ingredient list may not be all that it seems? According to Food Safety News, producers are sneaking lower quality ingredients into our food to save money. This type of food fraud is estimated to cost the global food industry $10 to $15 billion per year. If you think back to the Middle Ages, even our ancestors were consumed with cost savings by inserting nutshells, seeds, berries, and more within their spices.
Using Mass Spectrometry to Screen Hundreds of Known and Unknown Metabolites
In the field of metabolomics, you typically choose to identify and characterize as many compounds as possible in an unbiased fashion, or screen for a specific set of compounds that are biologically relevant to your research. The beauty of the TripleTOF® System is that...
MultiOmics Research For the Study of Placental Development
A recent study by Katy Williams (UCSF), Christie Hunter (SCIEX), and Andrew Olsen (Advaita) used the iPathwayGuide within the OneOmics cloud computing environment to help understand how placental development can go awry during certain pregnancy complications such as pre-eclampsia.
This LC-MS/MS Application Detects Almond and Peanut Allergens in Spices
If you suffer from peanut allergies, you may want to think twice before diving into a bowl of something spicy. The reason being, some shipments of North American and European products containing ground cumin, cumin powder, cayenne pepper, paprika, and pilli-pilli...
Mass Spectrometry Detects Very Low Levels of Chemical Compounds in Asia Pacific Waters
Did you know that even though most of the world is covered in water, access to clean drinkingwater remains a problem? Take Asia for example where 62,000 people have lost their lives between 2001 and 2005 due to water-related disaster and illness. Clean water is...
Simultaneously Detect Different Types of Beer Microbes Using XP-PCR
Spoiler Alert – How to Save Time Testing for Bacteria in Beer? Nothing ruins a batch of beer worse than bacteria, specifically Pediococcus and Lactobacillus. Too much of these hop resistant genes can get carried away causing spoilage and sour beer. It is why breweries...