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A rising star in food allergen research: proteomics of shellfish allergen

It’s important to know what you’re eating, especially if you suffer from a food allergy.

About 220 million people worldwide live with a food allergy.1 These numbers, along with the complexity and severity of conditions, continue to rise. In America, there are about 32 million food allergy sufferers—5.6 million of those are children under the age of 18.2.2 That’s 1 out of every 13 children, or about 2 in every classroom. From a financial perspective, the cost of food allergy childcare for US families is up to $25 billion

Routine cannabis screening is here. Will your lab reap the benefits?

by Paul Winkler | 0 Comments

Fast, accurate, and robust solution for routine commercial cannabis testing

As the world debates cannabis legalization for therapeutic applications and recreational use, the trends are shifting. Medicinal use of cannabis is legal in an increasing number of countries worldwide, including 33 states and the District of Columbia in the United States. Uruguay was the first country in the world to legalize the sale, cultivation, and distribution of cannabis in 2013. In the United States, Washington and Colorado were the first to fully legalize cannabis in 2012. By the end of 2019, 10 states have legalized recreational use for adults over the age of 21, with 64% of Americans favoring the move

Keep up with fentanyl and its analogs: Failure to do so is not an option.

by Pierre Negri | 0 Comments

Fentanyl is one of the most well-known synthetic opioids that has been in the spotlight lately—and not for good reasons. The World Drug Report 2019 reveals that there have been more than 47,000 opioid overdose deaths in the United States in 2017. This is an increase...

Hemp, marijuana, CBD and THC: what’s the difference?

by Paul Winkler | 0 Comments

Cannabis refers to a genus of flowering plants originating from Asia.1 It's also an umbrella term that includes both marijuana plants and hemp plants, among others. With the flurry of legalization across the United States, CBD and THC derived products have been thrown...

6 Signs it’s time for a new vendor

by Michael Wonski | Blogs, Instrument maintenance, Optimizing Performance, Technology

A lab’s success depends on many factors from instrument quality to efficient operations, including being partnered with the right vendor. A vendor is more than just a supplier. They should provide you with a high-level quality of support in maximizing the lifespan and performance of your systems, reducing downtime, enhancing ROI and more. How do you know if you’re partnered with the right one? Here are six signs it might be time to find someone new.

Selecting an LC-MS system for quantitation of pharmaceutical drug development

by Kirsten Craven | Blogs, Echo MS, Pharma, QTRAP / Triple Quad, ZenoTOF 7600 system

We understand you are busy, needing to prioritize running instruments, reporting results and managing your laboratory to meet deadlines. We created a solution guide to explain how SCIEX systems fit in the drug development pipeline to save you time evaluating options.

Celebrating customer experience: Insights from SCIEX leaders

by Philip Taylor | Biopharma, Blogs, Clinical, Environmental / Industrial, Food / Beverage, Forensic, Life Science Research, Pharma, Technology

Introduction Customer Experience Day (CX Day) is a special occasion for SCIEX, celebrated every first Tuesday in October. It’s a day dedicated to recognizing the incredible value of our customers and the relentless dedication of our associates who strive to make...

PFAS analysis in food: a robustness study in sensitivity and stability

by Holly Lee | Blogs, Environmental / Industrial, Food / Beverage, QTRAP / Triple Quad

The combination of per- and polyfluoroalkyl substances (PFAS) testing, trace-level regulatory requirements and complex MS applications can be intimidating. In a recent webinar, now available on demand, SCIEX PFAS expert Craig Butt demonstrated how the new SCIEX 7500+ system can help make PFAS testing easier.

Your success and voice go a long way!

by Philip Taylor | Biopharma, Blogs, Clinical, Environmental / Industrial, Food / Beverage, Forensic, Life Science Research, Pharma, Technology

At the heart of everything we do is ensuring that your workflows and team are empowered to achieve optimal results with your SCIEX instruments, software, consumables, and services. Every interaction with SCIEX is designed to support your success through the dedication...

LC-MS system replacement: Are you ready?

by Kirsten Craven | Blogs, Pharma, QTRAP / Triple Quad

Meeting deadlines in a bioanalysis laboratory can be a big challenge. Older, less sensitive and less reliable LC-MS systems make it even more difficult. Even the disruption caused by the installation and validation can be disconcerting and delay decisions. Does this sound familiar?

Understanding technical debt: the hidden cost of ignoring problems

by April Quinn-Paquet | Blogs, SCIEX OS software, Technology

In today’s rapidly evolving technological landscape, businesses heavily rely on software and IT systems to drive their operations. However, the pursuit of efficiency and speed often leads to the accumulation of what is known as technical debt. Technical debt refers to the implied cost incurred when businesses choose quick but limited solutions over better approaches that may take more time to implement. This blog post will delve into the concept of technical debt, its implications for businesses and how to avoid falling victim to its detrimental effects.

Optimized rolling collision energy curves for IDA and SWATH DIA for peptides

by Christie Hunter | Data acquisition, Life Science Research, Proteomics, QTOF, SCIEX information, ZenoTOF 7600 system

During data dependent acquisition (DDA or IDA) or SWATH acquisition, the collision energy can be automatically adjusted according to the mass/charge and charge of the peptide. This dependency has been well characterized on our QTOF systems. By selecting rolling...

Rescheduling a Schedule I substance, and the Delta-8 controversy

by Diana Tran | Blogs, Food / Beverage, Food and Beverage

Did you know that in the US, drugs and other chemicals are classified into 5 distinct categories depending on the drug’s acceptable medical use and its potential for abuse or dependency? Drugs federally classified as Schedule I substances by the US Drug Enforcement Administration (DEA) are considered to have the highest potential for abuse and for creating severe psychological and/or physical dependence. In addition to heroin, LSD and MDMA (ecstasy), cannabis is classified as a Schedule I substance in the Controlled Substance Act of 1970, which means it has no approved medical usage.

sMRM Pro Builder template tutorial

by Mackenzie Pearson | Data processing, Data Visualization, How-to videos, Life Science Research, Lipidomics, Metabolomics, Optimizing Performance, QTRAP / Triple Quad, Results

The sMRM Pro Builder template is an Excel-based tool that can help you implement large panels of analytes in your lab. The Excel sheet will take your preliminary experimental results and compute retention times, retention time window widths and dwell time weighting to optimize your targeted assay.

10 Minutes in One Shot. That’s How Quickly You Can Screen 664 Forensics Compounds

by SCIEX Community | Blogs, Forensic

Drug testing is a moving target. As novel psychoactive substances (NPS) rapidly emerge as a new class of designer stimulants (DS), global use has reached an all-time high over the last decade. Supposedly ‘legal’ alternatives to internationally controlled drugs, these...

Turbocharge THC-COOH Hair Analysis with Super Sensitive LC-MS/MS and Solid Phase Extraction

by SCIEX Community | Blogs, Forensic

Do you want a more efficient workflow for the forensic analysis of THC-COOH in hair samples? Yes! Do we know a simple, highly sensitive technique? You bet! Read on to find out how you can detect THC-COOH in hair down to 0.2 pg/mg trace concentration levels with...

Fast Novel Psychoactive Substance Testing, At Your Fingertips

by SCIEX Community | Blogs, Forensic

Why Dried Blood Spot Analysis Is the Way to Go for Novel Psychoactive Substances(And Why You Need This SCIEX LC-MS/MS Method) Anyone with children will remember that moment in the hospital when the nurse pricks the heel of your tiny new baby to squeeze out a few drops...

Take 5 with Dan Blake – 5 Minutes, 5 Questions on the World of Clinical Mass Spec

by SCIEX Community | Blogs, Clinical

We would like to formally (or informally) introduce the new SCIEX Clinical Diagnostics blog series entitled, Take 5. Every couple of months we will ask a member of our team to answer five questions and share their responses in a format you can read in five minutes. We...

The Technology Behind Safe, Legal Cannabis

by SCIEX Community | Blogs, Food / Beverage

The Third in a Three-Part Series Part 1: Cannabis is Legal in Canada - How Did We Get Here? Part 2: Canada's Focus on Cannabis Quality and Safety Intensifies Welcome to the third in a series of blogs from the cannabis team at SCIEX, designed to bring you up to speed...

What is Multi Attribute Methodology (MAM)?

by SCIEX Community | Biopharma, Blogs

Q&A with Sean McCarthy Global Market Manager, Biologics, SCIEX MAM is an acronym for Multiple Attribute Method. In short, MAM is a method which may be applied for characterization of a biotherapeutic to understand its sequence, identify liabilities, identify...

New Methods for N-Glycan Sequencing Provide Structural Information in as Little as 1 Hour

by SCIEX Community | Biopharma, Blogs

As interest in N-glycan analysis grows within the biopharma industry, innovation continues allowing analyses to be done in less time with fewer and less tedious, sample preparation steps. One of these recent innovations was the release of the SCIEX Fast Glycan...

When Chiral Separation Turns Tricky: The Story Behind CESI-MS in Forensic Chiral Analysis

by SCIEX Community | Blogs, Forensic

Against a backdrop of rapid growth, chirality plays a major role in the synthesis of drugs in both pharmaceutical and illicit drug development. In fact, more than half of the drugs currently in use are chiral compounds, available as either racemates or pure...

Cannabis is Legal in Canada – How Did We Get Here?

by SCIEX Community | Blogs, Food / Beverage

The First in a Three-Part Series Welcome to the first in a series of blogs from the cannabis team at SCIEX, designed to bring you up to speed and put you in the lead of the recently legalized cannabis market in Canada. The Canadian cannabis market has taken the plunge...

3 Dicamba Analysis Questions You Need to Ask Yourself Today

by SCIEX Community | Blogs, Environmental / Industrial, Food / Beverage

We blinked and the last two years went in a flash. It seems like just yesterday, the Dicamba herbicide controversy hit the headlines in 2016 and the EPA set the regulations to expire in two years. Fast forward to today. Dicamba is an acid herbicide used to kill...

Don’t Be a Food Scandal Scapegoat. Fight Back with LC-MS/MS for Your Meat Authenticity Testing

by SCIEX Community | Blogs, Food / Beverage

The infamous horsemeat scandal of 2013 shined a spotlight on the questionable integrity of our meat supply. What followed was a lengthy investigation as the extent of the scandal unraveled before our eyes, reaching far beyond the European borders...

It’s Time to Turn Things Around―Faster and Accurate Mass Analysis of Organic Explosives

by SCIEX Community | Blogs, Forensic

Sadly, the world is a volatile place. The threat of organic explosive use by terrorists and criminals is very much with us, posing a significant danger to people worldwide. The rising concern for public safety is a top priority for national security organizations...

Push Your Research to the Cutting Edge: 2018 Global CESI-MS Symposium

by Kelly May | Biopharma, Blogs, Life Science Research

There are a lot of conferences vying for your attention every year. The Global CESI-MS Symposium on October 10-11 in the Netherlands is one you can’t afford to miss. It is the place to hear about the latest advancements made through the adoption of CESI-MS...

Break the routine: SCIEX OS-MQ improves your quantitation workflows

by SCIEX Community | Blogs, Software, Technology

Advances in today’s technology have resulted in a need for higher and faster sample throughput, with increasing number of measured analytes per sample. The new SCIEX OS-MQ software breaks the routine and takes quantitation workflows to a new level. Key features...

Stop Fumbling Around in the Dark: Try LC-MS/MS for Designer Drugs in Forensic Samples

by SCIEX Community | Blogs, Forensic

Imagine being blindfolded, sent into a large (dark) room filled with obstacles and challenged to find an item, but you don’t know what that item is, and you have never seen it before. Then you must do the same again the next day, but you are looking for a different...

Something’s in the Water: Tackle Your PFAS Analysis

by Craig Butt | Blogs, Environmental / Industrial

Exposure to per- and polyfluoroalkyl substances (PFAS) residues could be dangerous. These chemicals have been linked to a variety of adverse health effects including liver damage, thyroid disease, decreased fertility, high cholesterol, obesity, hormone suppression,...

5 Reasons Why Mass Spec is Transforming Clinical Labs

by SCIEX Community | Blogs, Clinical

According to the American Clinical Laboratory Association, more than 7 billion clinical lab tests are performed in the U.S. every year. While mass spectrometry represents only a fraction of the clinical applications, there are a growing number of tests where mass...

Save Effort. Save Time. Consolidate Your BioTherapeutic Quality, Safety, and Efficacy Assessments with One Direct LC-MS MAM Assay.

by SCIEX Community | Biopharma, Blogs

In a previous blog, we learned how you could Simplify Your Life with a Streamlined Workflow for Multiple Attribute Methodology (MAM). Based on the well-known technique of peptide mapping, a Liquid Chromatography-Mass Spectrometry-based MAM workflow (LC-MS MAM) enables...

Metabolism and Biotransformation – What Are You Missing?

by SCIEX Community | Blogs, Pharma

Are you looking to improve your MetID studies? Want to achieve the productivity and throughput you need to keep your projects moving and have complete confidence that you’re not missing any low level or parent-like metabolites in your sample? In this blog, we’re...

Biologics Characterization: Intact and Subunit Mass Analysis

by SCIEX Community | Biopharma, Blogs

When All You Need Is Range – Mass Range, Dynamic Range, and the Complete Range Launching the best possible product in the shortest time possible is key for pharmaceutical companies like you. As you know, nearly every process throughout the biologics development cycle...

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Routine cannabis screening is here. Will your lab reap the benefits?

Keep up with fentanyl and its analogs: Failure to do so is not an option.

Hemp, marijuana, CBD and THC: what’s the difference?

6 Signs it’s time for a new vendor

Selecting an LC-MS system for quantitation of pharmaceutical drug development

Celebrating customer experience: Insights from SCIEX leaders

PFAS analysis in food: a robustness study in sensitivity and stability

Your success and voice go a long way!

LC-MS system replacement: Are you ready?

Understanding technical debt: the hidden cost of ignoring problems

Optimized rolling collision energy curves for IDA and SWATH DIA for peptides

Rescheduling a Schedule I substance, and the Delta-8 controversy

sMRM Pro Builder template tutorial

10 Minutes in One Shot. That’s How Quickly You Can Screen 664 Forensics Compounds

Turbocharge THC-COOH Hair Analysis with Super Sensitive LC-MS/MS and Solid Phase Extraction

Fast Novel Psychoactive Substance Testing, At Your Fingertips

Take 5 with Dan Blake – 5 Minutes, 5 Questions on the World of Clinical Mass Spec

The Technology Behind Safe, Legal Cannabis

What is Multi Attribute Methodology (MAM)?

New Methods for N-Glycan Sequencing Provide Structural Information in as Little as 1 Hour

When Chiral Separation Turns Tricky: The Story Behind CESI-MS in Forensic Chiral Analysis

Cannabis is Legal in Canada – How Did We Get Here?

3 Dicamba Analysis Questions You Need to Ask Yourself Today

Don’t Be a Food Scandal Scapegoat. Fight Back with LC-MS/MS for Your Meat Authenticity Testing

It’s Time to Turn Things Around―Faster and Accurate Mass Analysis of Organic Explosives

Push Your Research to the Cutting Edge: 2018 Global CESI-MS Symposium

Break the routine: SCIEX OS-MQ improves your quantitation workflows

Stop Fumbling Around in the Dark: Try LC-MS/MS for Designer Drugs in Forensic Samples

Something’s in the Water: Tackle Your PFAS Analysis

5 Reasons Why Mass Spec is Transforming Clinical Labs

Save Effort. Save Time. Consolidate Your BioTherapeutic Quality, Safety, and Efficacy Assessments with One Direct LC-MS MAM Assay.

Metabolism and Biotransformation – What Are You Missing?

Biologics Characterization: Intact and Subunit Mass Analysis

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